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丁卡因_CAS:94-24-62018-01-22
产品属性

CAS号:94-24-6

重量(克):1000kg

价格(元):询价

时间:2018-01-22 15:43:16

交易状态:等待报价

产品信息
丁卡因

化合物简介

Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
Tetracaine is the T in TAC, a mixture of 5 to 12 per cent tetracaine, 0.05 per cent adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
A systematic review investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties. However, it did not find an improvement in first attempt cannulations.

基本信息

中文名称:
丁卡因
中文别名:
4-(丁氨基)-苯甲酸 2-(二甲氨基)乙酯;

野生白屈菜提取物;

2-(二甲基氨)乙基4-(正丁基氨基)苯甲酸酯;

英文名称:
tetracaine
英文别名:
Tetracaina;

Amethocaine;

Uromucaesthin;

Tetracainum;

Contralgin;

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CAS号:
94-24-6
分子式:
C15H24N2O2
分子量:
264.36300
精确质量:
264.18400
PSA:
41.57000
LogP:
2.69000

分析方法

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共找到 12 个分析方法

柱型 活性相 温度 (°C) 保留指数 (I) 参考文献
填充柱 SE-30 2215. Perrigo and Peel, 1981
柱型 活性相 温度 (°C) 保留指数 (I) 参考文献
填充柱 SE-30 2219. MHA, 9999

物化性质

外观与性状:
白色结晶粉末
密度:
1.044 g/cm3
沸点:
389.4ºC at 760 mmHg
闪点:
189.3ºC
折射率:
1.537
储存条件:
库房通风低温干燥,与食品原料类分开存放

安全信息

  • 海关编码:2922499990
  • 危险品运输编码:UN 2811
  • 危险类别码:R22; R40; R42/43
  • 安全说明:S22-S36/37
  • RTECS号:DG4725000
  • 危险品标志:Xn

生产方法及用途

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用途

生化研究。

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