此反应是指邻胺基醛或酮与另一分子有α-亚甲基的酮反应得到喹啉的反应。反应中胺酮缩合，得到的中间体经过酸或碱催化环脱水得到喹啉。
反应机理：
最新文献
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Transition-Metal-Free Indirect Friedländer Synthesis of Quinolines from Alcohols
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Silver Phosphotungstate: A Novel and Recyclable Heteropoly Acid for Friedländer Quinoline Synthesis
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Synthesis of Quinolines via Friedländer Reaction in Water and under Catalyst-Free Conditions
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One-Pot Friedländer Quinoline Synthesis: Scope and Limitations
A.-H. Li, D. J. Beard, H. Coate, A. Honda, M. Kadablbajoo, A. Kleinberg, R. Laufer, K. M. Mulvihill, A. Nigro, P. Rastogi, M. W. Siu, A. G. Steinig, T. Wang, D. Werner, A. P. Crew, M. J. Mulvihill, Synthesis, 2010, 1629-1632.
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Solvent-Free Enantioselective Friedländer Condensation with Wet 1,1′-Binaphthalene-2,2′-diamine-Derived Prolinamides as Organocatalysts
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