Barton-Pinhey芳基化反应 – 化学慧

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Barton-Pinhey芳基化反应 – 化学慧

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芳基三乙酸铅和含有NH的胺或芳环进行偶联的反应。此反应可作为

Chan–Lam反应的替代反应。除了亲核的胺或芳环能发生反应，富电子的芳环也可以进行偶联。

反应机理

反应实例

【Organic letters, 2000, 2, 3055-3057】

【Synlett, 2006, 15, 2375-2378】

【Journal of Organic Chemistry, 1996, 61, 5865-5870】

编辑自：reactionflash

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