化合物简介
Pyrantel pamoate (under US Pharmacopoeia) or pyrantel embonate (under European Pharmacopoeia), is used as a deworming agent in the treatment of hookworms (all species) and roundworms (Ascaris lumbricoides, aka ascarids in humans) in domesticated animals such as horses, cattle, sheep, pigs, cats, dogs, and many other species. It is a combination of pyrantel and pamoic acid. Some drug companies pair pyrantel pamoate with praziquantel for tapeworms, and sometimes febantel for whipworms in order to provide more complete treatment for intestinal parasites in one dose.
It is also used for pinworm treatment. There are a number of brands, including “Reese’s Pinworm Medicine”, “Pin-X”, “Pin-Rid”,”PYRANTRIN” formally called “COMBANTRIN”, “Anthel”, “Helmintox”, “Helmex” and Drontal Cat.
Pyrantel pamoate is also commonly included in monthly administered chewable heartworm preventative tablets for dogs.
It is also used for pinworm treatment. There are a number of brands, including “Reese’s Pinworm Medicine”, “Pin-X”, “Pin-Rid”,”PYRANTRIN” formally called “COMBANTRIN”, “Anthel”, “Helmintox”, “Helmex” and Drontal Cat.
Pyrantel pamoate is also commonly included in monthly administered chewable heartworm preventative tablets for dogs.
基本信息
- 中文名称：
- 双羟萘酸噻嘧啶
- 中文别名：
- (E)-1-甲基-2-[2-(2-噻吩基)乙烯基]-1,4,5,6-四氢嘧啶 4,4′-亚甲基-双(3-羟基2-奈酸)盐;
双羟乃酸噻嘧啶;
- 英文名称：
- 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
- 英文别名：
- Pyrantel pamoate;
Embovin;
CP-10,423-16;
EINECS 244-837-1;
UNII-81BK194Z5M;
查看更多英文别名
- CAS号：
- 22204-24-6
- 分子式：
- C34H30N2O6S
- 分子量：
- 594.67700
- 精确质量：
- 594.18200
- PSA：
- 158.90000
- LogP：
- 6.26020
物化性质
- 外观与性状：
- 无气味的淡黄色至黄褐色的结晶粉末无味道
- 熔点：
- 266-267ºC
- 沸点：
- 642.7ºC at 760 mmHg
- 闪点：
- 356.5ºC
- 储存条件：
- 0-6ºC
- 蒸汽压：
- 2.13E-17mmHg at 25°C
安全信息
- 海关编码：2934999090
