| 1,4,8,11-四氮杂环十四烷 | 1,4,8,11-TETRAAZACYCLOTETRADECANE | 295-37-4 |
化合物简介
Cyclam (1,4,8,11-tetraazacyclotetradecane) is an organic compound with the formula (NHCH2CH2NHCH2CH2CH2)2. It is a white solid that is soluble in water. The compound is notable as a macrocyclic ligand, which binds strongly to many transition metal cations. The compound was first prepared by the reaction of 1,3-dibromopropane and ethylenediamine.
The compound features four secondary amines. Its complexes therefore can exist as several diastereomers, depending on the relative orientation of the N–H centres. Its complexes feature alternating five- and six-membered chelate rings. The closely related ligand cyclen ((CH2CH2NH)4) forms only five-membered C2N2M chelate rings and tends not to form square-planar complexes.
Isomers of a square planar metal cyclam complex.
The compound features four secondary amines. Its complexes therefore can exist as several diastereomers, depending on the relative orientation of the N–H centres. Its complexes feature alternating five- and six-membered chelate rings. The closely related ligand cyclen ((CH2CH2NH)4) forms only five-membered C2N2M chelate rings and tends not to form square-planar complexes.
Isomers of a square planar metal cyclam complex.
基本信息
- 中文名称：
- 1,4,8,11-四氮杂环十四烷
- 中文别名：
- 环拉胺;
1,4,8,11-四氮环十四烷;
- 英文名称：
- 1,4,8,11-tetraazacyclotetradecane
- 英文别名：
- JM 1498;
1,4,8,11-tetrazacyclotetradecane;
14-crown-4N4;
Cyclam;
EINECS 206-039-1;
查看更多英文别名
- CAS号：
- 295-37-4
- 分子式：
- C10H24N4
- 分子量：
- 200.32400
- 精确质量：
- 200.20000
- PSA：
- 48.12000
- LogP：
- 0.45380
物化性质
- 外观与性状：
- 白色松软的针状结晶粉末
- 密度：
- 0.861g/cm3
- 熔点：
- 184-186 °C(lit.)
- 沸点：
- 321.1ºC at 760mmHg
- 闪点：
- 153ºC
- 蒸汽压：
- 0.000305mmHg at 25°C
安全信息
- 符号：
GHS07 - 信号词：警告
- 危害声明：H315; H319; H335
- 警示性声明：P261; P305 + P351 + P338
- 海关编码：2933990090
- WGK Germany：3
- 危险类别码：R36/37/38
- 安全说明：S26-S36
- RTECS号：XA5254800
- 危险品标志：Xi
生产方法及用途
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用途
普乐沙福中间体。
