主要规格98%
化合物简介
Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication.
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer.
Ethyl oleate is regulated as a food additive by the Food and Drug Administration under “Food Additives Permitted for Direct Addition to Food for Human Consumption”, 21CFR172.515.
Ethyl oleate has been identified as a primer pheromone in honeybees.
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. There is a growing body of research literature that implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, and brain). Among the speculations is that ethyl oleate may be the toxic mediator of alcohol in fetal alcohol syndrome. The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion. Ethyl oleate is not currently approved by the U.S. Food and Drug Administration for any injectable use. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed.
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer.
Ethyl oleate is regulated as a food additive by the Food and Drug Administration under “Food Additives Permitted for Direct Addition to Food for Human Consumption”, 21CFR172.515.
Ethyl oleate has been identified as a primer pheromone in honeybees.
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. There is a growing body of research literature that implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, and brain). Among the speculations is that ethyl oleate may be the toxic mediator of alcohol in fetal alcohol syndrome. The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion. Ethyl oleate is not currently approved by the U.S. Food and Drug Administration for any injectable use. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed.
基本信息
- 中文名称：
- 油酸乙酯
- 中文别名：
- 顺-9-十八烯酸乙酯;
油酸乙基酯;
9-十八烯酸乙酯;
(Z)-9-十八烯酸乙酯;
十八烯酸乙酯;
- 英文名称：
- ethyl oleate
- 英文别名：
- ethylis oleas;
ETHYLOLEATE,NF;
ETHYL OLEATE;
Ethylis oleas,Oleic acid ethyl ester;
Oleic acid ethyl;
查看更多英文别名
- CAS号：
- 111-62-6
- 分子式：
- C20H38O2
- 分子量：
- 310.51500
- 精确质量：
- 310.28700
- PSA：
- 26.30000
- LogP：
- 6.58700
物化性质
- 外观与性状：
- 透明淡黄色油性液体
- 密度：
- 0.87 g/mL at 25 °C(lit.)
- 熔点：
- −32 °C(lit.)
- 沸点：
- 216-218 °C15 mm Hg
- 闪点：
- >230 °F
- 折射率：
- n20/D 1.451(lit.)
- 储存条件：
- -20ºC
- 蒸汽压：
- 3.67E-06mmHg at 25°C
安全信息
- 海关编码：2916150000
- WGK Germany：2
- 安全说明：S23-S24/25
- RTECS号：RG3715000
生产方法及用途
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生产方法
1.由油酸与乙醇酯化而得。将硫酸加入油酸的乙醇溶液中,加热回流10小时。冷却,用甲醇钠中和至pH8-9,用水洗至中性,加无水氯化钙干燥,过滤,得油酸乙酯。
用途
1.主要用作润滑剂、抗水剂、溶剂、油质载体和合成树脂韧化剂等。作为化学试剂,主要用作气相色谱固定液(最高使用温度120℃)。
2. 可用于日化香精及食用香精配方中。常用于烘烤食品、冰冻乳制品、饮料。
