化合物简介
A potent O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. The authors anticipate that Thiamet-G will find wide use in probing the functional role of O-GlcNAc in vertebrate brain, and it may also offer a route to blocking pathological hyperphosphorylation of tau in AD. Anti-Alzheimer’s agent.
基本信息
- 中文名称：
- Thiamet G
- 英文名称：
- 2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
- 英文别名：
- Thiamet G0nDiscontinued;
Thiamet G;
Thiamet G;
- CAS号：
- 1009816-48-1
- 分子式：
- C9H16N2O4S
- 分子量：
- 248.29900
- 精确质量：
- 248.08300
- PSA：
- 119.61000
